DNA
Liquid biopsy research
Investigate epidermal growth factor receptor (EGFR) mutations and circulating tumor DNA (ctDNA) in plasma and saliva.
Explore EGFR researchAPPLICATIONS
EFIRM research applications.
Explore EFIRM (Electric Field-Induced Release and Measurement) research across molecular targets and specimen types. Each application uses a target-specific assay and validation protocol.
Ab
Autoantibody studies
Published studies measure autoantibodies associated with Sjögren’s syndrome in people with the condition and in people with dryness symptoms. Explore the anti-SSA/Ro antibody study.
Read autoantibody studiesRNA
Pathogen biomarker research
Research workflows investigate viral RNA, antigen and antibody signals in saliva.
Read pathogen researchμ
New biomarker feasibility
Discuss nucleic acid or protein assay development with target-specific recognition and controls.
Discuss a new targetΔ
Longitudinal research
Case studies investigate molecular signals over time. Clinical utility requires further evidence.
Review the evidenceAu
Electrochemical method development
Explore probe chemistry, matrix effects and measurement methods in a defined research protocol.
Explore the technologyApplication areas are research directions, not cleared diagnostic indications or guarantees of assay availability. Translation to patient testing requires appropriate validation and review.
MITOCHONDRIAL DNA · RESEARCH DIRECTION
Measure selected mtDNA targets
without copying the DNA.
Published meat-species research demonstrates direct, PCR-free measurement of selected mitochondrial DNA targets after sample treatment.
A defined starting point
Species-specific recognition provides evidence for a particular food-identity assay. It does not establish a validated disease test or performance for every mitochondrial sequence.
New research questions
Discuss selected mitochondrial sequences, variants and heteroplasmy research with a target-specific assay plan. These are research directions requiring new feasibility and validation work.
Build the controls
Assess sample preparation, specificity against nuclear mitochondrial DNA sequences (NUMTs), controlled mixture gradients and independent comparison methods.
TECHNOLOGY → CAPABILITY → APPLICATION
Different targets.
A common platform logic.
Published examples span human biomarkers, vesicle-associated signals, food authenticity and agricultural testing.
Selected EGFR mutations
Complementary capture and detector probes connect selected mutation sequences to PCR-free electrochemical measurement.
Evidence & stage
Human cohort research; selected variants. Further analytical characterization was published in 2020.
Exosome-associated biomarkers
Magnetic beads enrich exosomes before electric-field-assisted release of RNA for capture. A surface-associated protein marker is measured without vesicle rupture. Electrical release provides target access; the beads perform separation.
Evidence & stage
Foundational laboratory and mouse-model research. Release is part of this assay, rather than every EFIRM workflow.
Multiple viral biomarker classes
Four separate assays connect distinct recognition chemistries to an electrochemical platform. The viral RNA workflow includes isothermal amplification (RT-LAMP) and restriction digestion.
Evidence & stage
Separate singleplex research assays, with assay-specific preparation. The neutralizing-antibody assay is competitive; higher antibody activity gives lower current. Not a clinical indication or current kit specification.
Meat species identification
Species-specific DNA recognition connects meat identity research to PCR-free electrochemical readout, with sample treatment before measurement.
Evidence & stage
Published food-authenticity research. A route to species identification studies beyond human biomarkers.
Transgenic soybean identification
Event-specific DNA recognition is evaluated against real-time PCR in a blinded soybean cargo study.
Evidence & stage
Published research by external academic and food-testing groups. Event-specific evidence, rather than a universal GMO assay.
Salivary autoantibodies
Antibody assays extend the recognition chemistry beyond nucleic acid hybridization.
Evidence & stage
Research in two Danish cohorts. Read the associated corrigendum with the original study.
These are published research applications across different assay configurations. They do not establish current EFIRM96 specifications, kit availability or diagnostic authorization. Explore the publication library for authors, methods and study scope.
Browse the publication library →RESEARCH & ASSAY DEVELOPMENT
Bring a target.
Build the next application.
EZLife Bio’s development experience extends beyond liquid biopsy, connecting sequence recognition and protein assays with different research questions.
ALDH2 variant detection
Development work addresses the ALDH2 rs671 G→A variant. The patent-described example uses DNA extraction and PCR amplification before EFIRM hybridization and electrochemical measurement.
A genetic-variant development example; a patent describes a method, rather than clinical validation or current kit availability.
Explore the method ↗Protein assay development
AMH has been a focus of EZLife Bio’s protein-assay development. Antibody-based recognition offers a route to connect a protein target with the electrode platform.
Discuss your target, specimen, reference materials and validation needs with the development team.
Discuss protein research →Sequence & variant research
Research directions include MTHFR variants, expanded mutation panels and selected viral sequences, alongside published EGFR, meat-species and soybean applications.
Protein & antibody research
Development directions include CA125, HE4 and AMH. Published antibody studies illustrate another recognition strategy within the electrochemical platform.
Food & agricultural research
Species identification, transgenic-event detection and food authenticity offer routes for collaboration with researchers and testing laboratories.
Development directions require target-specific feasibility and validation. For compatible platform configurations or a new assay project, contact EZLife Bio.
Discuss your application →What question will you bring?
Discuss your research goals, platform needs or a new scientific collaboration.