EZLife Bio is an upstream technology platform company. EFIRM (Electric Field-Induced Release and Measurement) connects EFIRM96 instruments, EPLATE consumables and software for research and target-specific assay kit development.
Field-assisted recognition. Electrochemical measurement.Research use only Not for diagnostic procedures
01 / THE PLATFORM
One platform. Three core products.
Use the platform for molecular research or build your own target-specific assay kits, combining recognition chemistry with instrumentation, electrode consumables and software.
An applied electrical waveform polymerizes a conducting-polymer layer at the gold working electrode, incorporating capture probes at the sensing interface. Published nucleic acid methods use polypyrrole (PPy).
The electrode, polymer and molecular probes form one functional interface. This schematic illustrates a published nucleic acid assay; surface formulations vary by method.
Published nucleic acid assay schematic · not to scale. Molecular motion and the current trace illustrate the mechanism. Release and sample preparation are assay-specific; washes and controls are omitted from the drawing.
PCR-free target detection
Enzyme-mediated signal generation is distinct from copying DNA. Chemistry, sample preparation and performance depend on the assay and its validated protocol.
03 / THE EVIDENCE
The science moves forward. Follow the research.
Selected EFIRM and related liquid biopsy publications across research groups. Original studies and reviews are identified separately, with their limits in view.
Investigates four separate electrochemical assays for viral RNA, antigen, binding antibody and neutralizing antibody signals in saliva.
Separate singleplex tests, rather than four targets measured simultaneously in one well. The viral RNA workflow includes RT-LAMP amplification and restriction digestion; antibody assays use distinct preparation and readout conditions. Not a clinical testing authorization.
Investigates PCR-free mitochondrial DNA recognition for meat species identification using an electrochemical assay.
Food-sample research with assay-specific sample treatment. Not preparation-free, a universal species panel or a current kit specification. Read the associated corrigendum.
Existing EFIRM96 instruments, EPLATE consumables and instrument software are available for delivery.
Order planning & delivery
Larger orders may require contract manufacturing. Lead times depend on order size, configuration and production arrangements and are confirmed during quotation.
Included with the instrument
Instrument purchase includes software for use on that instrument only, training and general technical support.
Develop a method together
For assay-development guidance, we prioritize discussing collaboration; paid support may also be arranged on a project-by-project basis.
Measure selected mtDNA targets without copying the DNA.
Published meat-species research demonstrates direct, PCR-free measurement of selected mitochondrial DNA targets after sample treatment.
A defined starting point
Species-specific recognition provides evidence for a particular food-identity assay. It does not establish a validated disease test or performance for every mitochondrial sequence.
New research questions
Discuss selected mitochondrial sequences, variants and heteroplasmy research with a target-specific assay plan. These are research directions requiring new feasibility and validation work.
Build the controls
Assess sample preparation, specificity against nuclear mitochondrial DNA sequences (NUMTs), controlled mixture gradients and independent comparison methods.
Our research thesis: reliable longitudinal molecular data is a critical missing layer for future AI-enabled health research.
TODAY · THE LABORATORY PLATFORM
Establish useful measurements
EFIRM96, EPLATE and software provide a laboratory platform for research and assay development. An automated prototype is available for demonstration and discussion with investment organizations and CLIA laboratories. It is a prototype, not a commercially available or clinically validated product.
FUTURE · SMALLER HARDWARE
Explore accessible sampling
Electrical control and current readout offer a route to miniaturization. Our longer-term goals include handheld instruments and smartphone modules, paired with appropriately validated assays.
FUTURE · LONGITUDINAL RESEARCH
Connect biology over time
Repeated saliva sampling could support molecular observations across time and physiological states. Carefully designed cohorts and reproducible measurements could create a data layer for future model-based research.
The path requires hardware development, assay validation, longitudinal studies and responsible data analysis. Handheld and smartphone products, continuous monitoring and AI-based clinical interpretation are future research goals.
