EGFR Mutation Kit (L858R, T790M, Exon19 Del)




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Description

Epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase protein that is expressed in some epithelial, mesenchymal and neurogenic tissue. Overexpression of EGFR has been reported to link to many tumors including non-small cell lung cancer (NSCLC). Studies have shown that EGFR expression in NSCLC is associated with reduced survival, lymph node metastasis and decreased chemosensitivity. EZLife Bio's EFIRM EGFR test kit allows for rapid direct detection of EGFR mutations directly from 20 uL biofluid specimen without purification and amplification steps.

Test Overview


Ezlife Bio’s EFIRM EGFR kit is an EFIRM assay that uses mutation specific probes to identify the presence of three EGFR mutations. The test workflow involves three simple steps which can be completed in approximately 2 hours from sample to answer:

  1. Direct sample addition: Apply just 20 ul of plasma or saliva sample into each well
  2. Reporter enzyme addition: Add prepackaged reporter enzymes to each well
  3. Measurement using the EFIRM 96 EReader: Add an enzyme substrate and perform electrochemical readout in all wells in <2 minutes




















EFIRM96 Detection Device


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Description

The EFIRM96 Detection device is a high-throughput analysis system for performing detection of biomolecules at the nanoamp scale. Precision-tuned in Silicon Valley and optimized through multiple clinical evaluations, the EFIRM96 device is highly sensitive, robust, and easy to use. The device is your one-stop solution for detection of a wide variety of biomarkers (microRNA, ctDNA, protein, small molecules, enzymes, nanomaterials) on a single system. The EFIRM96 Detection Device has been certified by CE as an IVD instrument and has been rigorously tested according to NRTL safety standards.

Features


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