ADVANTAGES

1

SIMPLE

No traditional techniques such as  extraction

or PCR amplification required.

2

RAPID

Measurements in as little as 30 minutes

3

VERSATILE

MicroRNA,DNA,Protein on the same platform.

4

SENSITIVE

>95% Concordance with traditional detection methods.

5

CONNECTED

Platform is cloud-integrated and allows for

automated report generation.

6

INTUITIVE

Easy to use software and support services are available.

EFIRM vs. PCR

 EFIRMPCR/Sequencing
Detection PrincipleEnlargement of gene detection signals by enzymatic electrochemical reactions rather than amplification of genesIncreasing the number of target gene fragments by PCR to increase the detection signal
Multi-target
Detection Capability
Can realize the joint detection of nucleic acid (DNA, RNA) and protein, RNA detection does not require reverse transcription reactionOnly nucleic acids can be detected. Reverse transcription to cDNA is required when detecting RNA
Detection SignalDirect detection of current signals without expensive optical acquisition systems, easy maintenanceRequires a fluorescent signal acquisition system, the system is complex, and maintenance is tedious
Sample ProcessingNo need for gene extraction, direct detectionGene extraction required, detection after amplification
SensitivitySensitivity increases with shorter gene fragmentsSensitivity decreases with shorter gene fragments and decreases detection efficiency for short fragments
Easy To OperateSimple, low operator requirementsComplex and demanding of operators
Detection Time30-60minPCR usually takes 2~6h, second generation sequencing usually takes several working days
Anti-pollutionNo amplification step, no aerosol contamination, low false positive rateThere are amplification steps, there is aerosol contamination, prone to false positives
Laboratory Environment
Requirements
Ordinary laboratory for testing, no need to establish a clinical gene amplification laboratoryNeeds a dedicated gene amplification laboratory that requires professional planning and construction
Reagent And
Equipment Costs
Electrochemical technology detects signals, reagents do not require fluorescent labeling, significantly reducing costsMany reagents use fluorescent markers. The equipment needs to be equipped with an optical acquisition system, which is expensive

APPLICATIONS

Medical

Tumor liquid biopsy

Cancer monitoring and screening

Agriculture

GMO screening

Infection testing

Inspection and quarantine

Contamination testing

Food quality inspection

Scientific research

Molecular biology

Electrochemical analysis

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